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Molecular, Cellular, and Tissue Engineering

Cornell Biomedical engineers are implementing multidisciplinary strategies, including expertise in materials science, cell biology, biochemistry, biomechanics, and biophysics, to engineer and analyze tissue dynamics and homeostasis. Faculty are developing approaches to recreate tissues that may be used as functional replacements, as models of diseased states, and for use in drug testing. Cornell’s world-class microscopy expertise and equipment, micro-fabrication resources within the Cornell NanoScale Science and Technology Facility, and top-ranked veterinary school and medical school synergize to create an ideal environment for research in molecular, cellular, and tissue engineering.

Faculty research summaries:

Prof. Jonathan Butcher’s lab is creating living 3D models of heart valve physiology and disease and using principles from developmental biology to drive the differentiation of stem/progenitor cells towards mature cardiac and valvular phenotypes. His lab has developed novel bioreactor technologies that apply multimodal defined mechanical stimulation to engineered tissue.

Prof. Claudia Fischbach-Teschl’s lab studies the effect of microenvironmental conditions on the prognosis and treatment of cancer patients. Her lab combines biomaterials, tissue-engineering and microfabrication strategies to develop pathologically relevant culture models for analysis of tumor-mediated angiogenesis, stroma remodeling, and bone metastasis.

Prof. Jan Lammerding’s lab is using a combination of microfluidics and micropatterning to create in vitro models of muscle differentiation and regeneration to study the effect of mutations that cause muscular dystrophies on the structure and function of muscle cells. Researchers in the lab are also applying cellular engineering approaches to investigate how changes in nuclear structure and mechanics can modulate cell migration in 3-D environments.

Prof. Michael Shuler’s lab builds microfludic systems that mimic the metabolism of drugs and chemicals in the human body. This “body-on-a-chip” device depends on constructing authentic tissue constructs to represent various organs such as the gastrointestinal tract.

Research Area Faculty

  Name Department Contact
lb244.jpg Bonassar, Lawrence
Professor
Biomedical Engineering, Mechanical and Aerospace Engineering 149 Weill Hall
607 255-9381
jtb47.jpg Butcher, Jonathan T.
Associate Professor, Associate Director of BME, Director of Undergraduate Studies
Biomedical Engineering 304 Weill Hall
607 255-3575
cc62_eng.jpg Chu, C. C.
Rebecca Q. Morgan '60 Professor
Fiber Science & Apparel Design 231 Human Ecology Building
607 255-1938
bdc68.jpg Cosgrove, Benjamin David
Assistant Professor
Biomedical Engineering 159 Weill Hall
607 255-7271
md255.jpg DeLisa, Matthew P.
William L. Lewis Professor of Engineering
Chemical and Biomolecular Engineering 254 Olin Hall
607 254-8560
cf99.jpg Fischbach-Teschl, Claudia
Associate Professor
Biomedical Engineering 157 Weill Hall
607 255-4547
jl2792.jpg Lammerding, Jan
Associate Professor, Director of Graduate Studies
Biomedical Engineering 235 Weill Hall
607 255-1700
dl79_eng.jpg Luo, Dan
Professor
Biological and Environmental Engineering
frm2.jpg Maxfield, Frederick
Professor, Chair
Biochemistry, Weill Cornell
mls50.jpg Shuler, Michael Louis
Samuel B. Eckert Professor of Engineering
Biomedical Engineering, Chemical and Biomolecular Engineering 350 Duffield Hall (secondarily 381 Kimball)
607 255-7577
ads10.jpg Stroock, Abraham Duncan
William C. Hooey Director and Gordon L. Dibble ’50 Professor of Chemical and Biomolecular Engineering
Chemical and Biomolecular Engineering 124 Olin Hall
607 255-4276
wrz2.jpg Zipfel, Warren R.
Associate Professor
Biomedical Engineering B41 Weill Hall
607 255-0663