BME7900 Seminar Series - David Mooney, PhD




We start off our Spring semester seminar series with Dr. David Mooney from Harvard. He is the Pinkas Family Professor of Bioengineering. Biomaterials to Enhance T Cell Cancer Therapies Abstract: T cell-based therapies are revolutionizing the treatment of some types of cancer, but currently suffer from a number of limitations. To address these challenges, we are developing biomaterials capable of concentrating, interrogating, and manipulating stem and immune cells ex vivo and in the body by controlling, in space and time, the interaction of the cells with various immunomodulatory cues. The development of artificial antigen presenting cells for the manufacturing and in vivo boosting of adaptive T cell-based therapies will be highlighted. Bio: David Mooney is the Pinkas Family Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences, and a Core Faculty Member of the Wyss Institute. His laboratory designs biomaterials to promote regeneration and immunotherapy. He is a member of the National Academy of Engineering, the National Academy of Medicine, and the National Academy of Inventors. His inventions have been licensed by over 15 companies, leading to commercialized products. He has founded companies, and is active on industrial scientific advisory boards.