Skip to main content

Warren R. Zipfel

wrz2-profile.jpg
  • Warren R. Zipfel
  • Dept: Biomedical Engineering
  • Title: Associate Professor
  • Address: B41 Weill Hall
  • Phone: 607 255-0663
  • return to list

Biography

My primary research focus is on the development and application of optical microscopy for biomedical research and for clinical imaging applications using nonlinear microscopy, endoscopy and laparoscopy. The biological research focus in my lab is in the area of optical detection of cancer, and collaborative studies in cancer biology using transgenic mouse models of ovarian, mammary and prostate cancer. I serve as Director of the Developmental Resource for Biophysical Imaging and Optoelectronics (DRBIO), the NIH-funded center that originally developed multiphoton imaging in 1990. My lab is also involved in numerous optical instrumentation development projects and the creation of new bioanalytical methods for studies in cell signaling and regulation.

Research Interests

My engineering research focus is on the development and application of optical microscopy for biomedical research and for clinical imaging applications, with a primary effort on nonlinear microscopy. I serve as Director of the Developmental Resource for Biophysical Imaging and Optoelectronics (DRBIO), the NIH-funded center that originally developed multiphoton imaging in 1990. My lab is involved in numerous optical instrumentation development projects and the creation of new bioanalytical methods for studies in cell signaling and regulation. The biological research focus in my lab has been in the areas of optical detection of cancer, and collaborative studies in cancer biology, transcription and nuclear regulation and in neurobiology.

Selected Publications

  • Song, A., H. Gao, A. Singh, Warren R Zipfel 2013. "Accurate EMCCD Photoelectron Calibration for Single Molecule Imaging Techniques." Philadelphia, PA
  • Khan, I., R. Gillilan, I. Kriksunov, R. Williams, Warren R. Zipfel, U Englich. 2012. "Confocal microscopy on the beamline: novel three-dimensional imaging and sample positioning." J Appl Crystallogr 45 (5): 936-943.
  • O'Dell, R S., C J. Ustine, D A. Cameron, S M. Lawless, R M. Williams, Warren R. Zipfel, E C Olson. 2012. "Layer 6 cortical neurons require Reelin-Dab1 signaling for cellular orientation, Golgi deployment, and directed neurite growth into the marginal zone." Neural Dev 7: 25.
  • Jain, M., B D. Robinson, D S. Scherr, J. Joshua Sterling, M. Ming-Ming Lee, J. Wysock, M A. Rubin, F R. Maxfield, Warren R. Zipfel, W W. Webb, S Mukherjee. 2012. "Multiphoton microscopy in the evaluation of human bladder biopsies." Arch Pathol Lab Med 136 (5): 517-26.
  • Shui, B., Abdullah Ozer, Warren R. Zipfel, N. Sahu, A. Singh, John T. Lis, Hua Shi, Michael I Kotlikoff. 2012. "RNA aptamers that functionally interact with green fluorescent protein and its derivatives." Nucleic Acids Research 40 (5): e39.

Websites

Education

  • BS (Biochemistry), Cornell University, 1987
  • Ph D (Biophysics), Cornell University, 1993