Claudia Fischbach-Teschl is an Associate Professor of Biomedical Engineering at Cornell University. She received her Ph.D. in Pharmaceutical Technology from the University of Regensburg, Germany and holds an M.S. in Pharmacy from the Ludwigs-Maximilians-University, Munich, Germany. She conducted her postdoctoral work at Harvard University in the Division of Engineering and Applied Sciences and joined the faculty of Cornell in 2007. Her research integrates bio-inspired engineering strategies and cancer research. Dr. Fischbach-Teschl is a project leader of Cornell's Physical Sciences in Oncology (PSOC) Center and a permanent member of the Tumor Microenvironment study section.
Microenvironmental conditions (e.g., 3-D cell-cell and cell-extracellular matrix interactions) are critically important in tumor induction and progression, and mediate the establishment of metastases at preferential target sites. By exploring tissue engineering, microfabrication, and biomaterials strategies the Fischbach-Teschl lab aims at elucidating microenvironmental events that play a role in these processes and to develop physical sciences-inspired approaches for more efficacious treatment of cancer. The three main areas of work in the Fischbach-Teschl lab focus on tumor angiogenesis, tumor-stem cell interactions, and bone metastasis. By elucidating the contributions of physical rather than biological aberrations to cancer development, progression, and therapy resistance, this work has the potential to dramatically change cancer diagnosis and treatment in the future.
- 2013. "Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche." Cancer Reseach 73 (23): 7079-89. .
- 2013. "In Vivo Tibial Compression Decreases Osteolysis and Tumor Formation in a Human Metastatic Breast Cancer Model." Journal of Bone and Mineral Research 28 (11): 2357-67. .
- 2012. "Implanted adipose progenitor cells as physicochemical regulators of breast cancer." Proc Natl Acad of Sci USA 109 (25): 9786-91. .
- 2011. "Hydroxyapatite Nanoparticle-containing scaffolds for study of breast cancer bone metastasis." Biomaterials 32 (22): 5112-22. .
- 2007. "Engineering tumors with 3D scaffolds." Nat Methods 4 (10): 855-60. .
Selected Awards and Honors
- Emerging Leaders Lecturer (University of Toronto, Department of Chemical Engineering and Applied Chemistry) 2014
- Humboldt Research Fellowship for Experienced Researchers (Max Planck Institute for Colloids and Interfaces in Potsdam, Germany) 2013
- Visiting Professor (Julius-Maximilians-Universität Würzburg, Wuerzburg, Germany) 2013
- Affinito Stewart Award (The President's Council of Cornell Women) 2010
- ORS Young Investigator (AAOS / ORS Molecular Biology and Therapeutics in Musculoskeletal Oncology (MBTMO) Meeting) 2008
- MS (Pharmacy), Ludwig Maximilians University, 1998
- Ph D (Pharmaceutical Technology), University of Regensburg, 2003