Putnam Group has Top 100 Paper for 2006
A paper published in Pharmaceutical Research and authored by Amy Richards-Grayson, Anne Doody and David Putnam of the Department of Biomedical Engineering and School of Chemical and Biomolecular Engineering, was ranked one of the Top 100 most downloaded manuscripts in the field of RNA-interference for 2006. The manuscript titled, “Biophysical and Structural Characterization of Polyethylenimine-Mediated siRNA Delivery in Vitro” focuses on defining the structure/function relationships that correlate polymer composition and architecture to nucleic acid delivery. siRNA is a potentially new therapeutic drug class, and the Putnam research group focuses on developing safe and effective means by which to deliver them to predetermined target cells.