Michael L. Shuler
James M. and Marsha McCormick Chair of Biomedical Engineering and Samuel B. Eckert Professor of Chemical Engineering
Department of Biomedical Engineering & Chemical and Biomolecular Engineering
The research conducted by Michael Shuler focuses on applying chemical reaction engineering principles to biological systems. As part of this work his research group has developed a new approach to model individual cells mathematically.
These models have proven to be important conceptual tools used to test hypotheses about cellular mechanisms and the interaction of viruses and cells. One model of a "minimal cell" is being used to relate genomic instructions to cell physiology.
Another project combines mathematical models of subcellular and cellular mechanisms with whole-animal models as a means to relate the rapidly increasing insight into molecular toxicology and pharmacology with animal physiology. The organs of mathematical models are compared with physical models that use living cells to mimic organs such as the liver and lung.
Dr. Shuler also is investigating targeted drug delivery to multidrug-resistant cancer cells.
Professor Shuler has been a member of the Cornell faculty since 1974 and has earned two teaching awards. He is a fellow of the American Institute of Medical and Biological Engineers for which he has served as vice president for education. He has received the Amgen Award in biochemical engineering and was elected to membership in the National Academy of Engineers and the American Academy of Arts and Sciences. He is on the editorial boards of four scientific journals.
Education
- Ph.D. 1973, University of Minnesota, Chemical Engineering
- B.S. 1969, University of Notre Dame, Chemical Engineering
